Human migration inhibitory factor: purification and immunochemical characterization.
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چکیده
منابع مشابه
Human migration inhibitory factor: purification and immunochemical characterization
Using gel filtration and preparative isotachophoresis, the migration inhibitory factor (MIF) was highly purified from human lymphocytes activated with concanavalin A. MIF is an acidic protein with a mol wt of approximately equal to 25,000 daltons as determined by gel filtration and analytical polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate. The protein inhibits migr...
متن کاملHuman Migration Inhibitory Factor: Purification and Immunochemical Characterization by Lutz H. Block,* Herbert Jaksche, Stephan Bamberger, and Gerhard
Products of activated lymphocytes are known to modulate the function of macrophages (1-3). Migration inhibitory factor (MIF) 1 is one of the best studied mediators of cellular immunity (4). Although many investigators have tried to analyze the biological and physicochemical properties of MIF from different species, the active substance has not been purified to homogeneity. MIF produced by guine...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1978
ISSN: 0022-1007,1540-9538
DOI: 10.1084/jem.147.2.541